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How we work

The Aperigon methodology.

A single methodology that produces a working system and a complete validation package as one set of artifacts. Five phases. Senior practitioners only.

Operating principles

Four commitments that shape every engagement.

PRINCIPLE 01

One team across implementation and validation

The configurators and the validators are the same people. There is no handoff from "build" to "validate." The traceability matrix is maintained from day one.

PRINCIPLE 02

Risk-based, CSA-aligned

We do not validate every feature to the same depth. We classify by patient-safety, product-quality, and data-integrity risk per FDA's 2025 CSA guidance and GAMP 5 Second Edition — then size the protocol accordingly.

PRINCIPLE 03

Written decisions, defensible rationale

Every configuration decision has a written rationale linked to a user requirement. Every test has a written acceptance criterion linked to a functional requirement. Every deviation has a written justification reviewed by quality.

PRINCIPLE 04

Defined phases with named deliverables

Each phase produces named, contractually-defined artifacts. Acceptance is binary. Phase boundaries are decision points: the work that's done is reviewed and signed off before the next phase begins.

The five phases

A complete engagement in five steps.

PHASE 01

Define

2 – 4 weeks

Stakeholder interviews, process mapping, user requirements specification, risk assessment, validation plan, project plan. The phase ends with an approved scope and a signed validation plan.

Deliverables: URS v1.0 · Risk Assessment v1.0 · Validation Plan v1.0 · Project Plan
PHASE 02

Design

3 – 6 weeks

Functional requirements specification, configuration specification, integration architecture, and the first version of the traceability matrix. By the end of this phase, every requirement is linked to a configuration decision and a planned test.

Deliverables: FRS v1.0 · Configuration Specification v1.0 · Integration Architecture v1.0 · Traceability Matrix v1.0
PHASE 03

Build

6 – 12 weeks

Configuration, integration development, data migration design, IQ protocol execution, end-user training development. The system is built, qualified at the installation layer, and ready for verification testing.

Deliverables: Configured environment · IQ Protocol & Report · Training Materials v1.0 · Traceability Matrix v2.0
PHASE 04

Verify

3 – 6 weeks

OQ protocol execution, PQ protocol execution, user acceptance testing, training delivery. The traceability matrix closes; every requirement is tied to a passed test.

Deliverables: OQ Protocol & Report · PQ Protocol & Report · UAT Sign-off · Training Records · Traceability Matrix v3.0 (final)
PHASE 05

Release

2 – 4 weeks

Cutover, hypercare, validation summary report, transition to managed services. The system is live, validated, and ready for inspection.

Deliverables: Production environment · Validation Summary Report · Hypercare Log · Periodic Review Template
What we don't do

A few things that won't happen on an Aperigon engagement.

Next step

See if we're a fit.

Tell us what's in flight. We'll respond personally — usually within a business day.

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